Scientists discover how neuroactive steroids dampen inflammatory signaling in cells

For the first time, scientists discovered how neuroactive steroids naturally found in the brain and bloodstream inhibit the activity of a specific kind of protein called Toll-like receptors (TLR4), which have been known to play a role in inflammation in many organs, including the brain. This UNC School of Medicine-University of Maryland collaboration, published in …

Sleep Patterns May Offer Clues to Alzheimer’s

HealthDay Reporter WEDNESDAY, Jan. 9, 2019 (HealthDay News) — Poor sleep is common among Alzheimer’s patients, and researchers say they’re beginning to understand why. Scientists studied 119 people aged 60 and older. Eighty percent had no thinking or memory problems, while the rest had only mild problems. The researchers found that participants with less slow-wave …

Higher risk of blood clots associated with some HRT tablets

Thursday, 10 January 2019 Some hormone replacement therapy (HRT) tablets appear to be associated with a higher risk of rare but serious venous thromboembolism (VTE), suggests a large study* published today in The BMJ. However, the study found no increased risk of VTE for HRT skin patches, gels or creams, although the vast majority of …

Things You Should Never Do to Your Skin

The Derm: Heidi Waldorf, M.D., Director of Laser And Cosmetic Dermatology, Mt. Sinai Hospital, New York City It was Jerry Seinfeld who gave dermatologists the “Pimple Popper M.D.” moniker. The truth is, Mr. Seinfeld, we express, drain, and extract, but, we never, ever pop. The difference lies in the details of semantics and technique. Squeezing …

Scientists design ‘smart’ wound healing technique

New research, published in the journal Advanced Materials, paves the way for “a new generation of materials that actively work with tissues to drive [wound] healing.” As more and more surgical procedures are performed in the United States, the number of surgical site infections is also on the rise. Chronic wounds that do not heal …