Doctors tell parents too late that their child is near death, survey suggests

Caroline White

Wednesday, 21 August 2019

Doctors may be telling parents too late that their child is near death, suggest the results of a small survey*, published online in the journal BMJ Supportive & Palliative Care.

National guidance is needed for doctors on how and when to give parents bad news, so that they can be properly prepared, say the researchers.

Open, accurate, and timely information about terminal illness and associated life expectancy are key tenets of high-quality palliative care. But previous research suggests that doctors often find it difficult and distressing to discuss end-of-life issues, they explain.

The researchers scrutinised a national Danish register of child deaths between 2012 and 2014 to find those who had died of a terminal illness: 402 out of 951.

A modified version of a validated questionnaire about the loss of a child was sent to the bereaved parents together with an explanatory leaflet about the nature of the study.

The questionnaire contained 122 questions designed to probe parents’ perceptions of the type and quality of communication with healthcare professionals throughout their child’s illness and imminent death.

In all, 136 mothers and 57 fathers completed the questionnaire, representing the parents of 152 children who had died of a terminal illness between 2012 and 2014 (response rate of 38%). Over half the children (56%) had died within the first year of life.

More than half the parents (59%) were told their child’s illness was terminal by a doctor. For around a third (30%) this was imparted immediately after the child’s birth.

But one in seven (15%) said they received this information in the last 24 hours of the child’s life. And around one in 10 (12%) said they weren’t told at all.

A similar proportion (11%) said they didn’t realise their child was going to die until the event itself. Around one in five (19%) only realised their child’s death was imminent a few hours beforehand.

Three out of four of the parents were satisfied with the information they were given by clinicians about their child’s illness. Most felt the same (80%) about their child’s treatment.

But the information given about how the child’s illness and treatment would affect their physical and mental health was judged inadequate by one in three (33%) and nearly half (48%), respectively.

A third (34%) of the parents weren’t told how to access end-of-life care, while four out of 10 (40%) didn’t know what to do in the event of an emergency.

Nearly all (98%) of them said that doctors should let parents know as soon as it was clear that all curative treatment options for their sick child had been exhausted.

Most parents (79%) felt the information about the terminal nature of their child’s illness had been provided in a timely manner. But more than four out of 10 (42%) said they were told too late that their child was about to die.

Nearly a third (31%) said they were unable to say goodbye to their child as they would have liked. And more than four out of 10 (43%) said that their child’s death had come as “a shock.”

This is a small observational study, and the distress of caring for a dying child might have affected parental recall, the researchers point out.

“Healthcare professionals are exposed to great challenges in communicating with parents about their children’s life limiting illness and imminent death, and even though [they] strive to communicate effectively with the children and their parents, several barriers on the sides of both parents and professionals, may hinder even the best of intentions,” they write.

“However, the present study clearly demonstrated that the parents’ need for information and support were not sufficiently met, and the study results may raise awareness of the importance of providing improved education and training for healthcare professionals working with children with life limiting diagnoses and their parents,” they conclude.

How to Strengthen Your Fingernails

Wear Gloves When Washing the Dishes

You probably can’t bow out of household chores entirely (a girl can dream!), but if you’re exposing your hands to water for long periods of time, like when you’re tackling a sink full of dishes, throw on a pair of rubber gloves first. Fingernails absorb water even better than your skin does, says Stern. And while that sounds like a good thing, it’s really not. “When water is constantly moving in and out of the nail, it puts a tremendous strain on the delicate nail cells,” she explains. Too much water contact can result in soft, weak nails that are susceptible to breakage.

Polish to Protect

Layers of nail polish help protect the fingernail and hold nail cells together, but Stern recommends a five-free formula that avoids dibutyl phthalate, toluene, formaldehyde, camphor, and formaldehyde resin chemicals. And whatever you do, don’t skip the base coat and topcoat—they provide two additional layers of protection that you don’t want to miss out on.

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Omega-3 supplements ‘no benefit’ to type 2 diabetics

Mark Gould

Thursday, 22 August 2019

People with type 2 diabetes “should not be encouraged” to take omega-3 fish oil supplements, researchers from the University of East Anglia say.

Writing in the BMJ* the authors say they carried out the most extensive systematic review of trials to date to assess effects of polyunsaturated fats on newly diagnosed diabetes and glucose metabolism, including previously unpublished data. They reviewed 83 studies and found no evidence of that supplements were either harmful or beneficial.

They found that long chain omega-3 had little or no effect on likelihood of diagnosis of diabetes or measures of glucose metabolism such as HbA1c, plasma glucose or fasting insulin, or homoeostatic model assessment for insulin resistance.

Dr Lee Hooper, who led the research, told the BBC there had been concerns omega-3 supplements might make glucose control more difficult. However, people with diabetes or who are at risk of developing it, can also have high levels of triglycerides – a type of blood fat – which omega-3 has been shown to reduce.

She said: “We found neither harm nor benefit.”

She described fish oil supplements as “really expensive stuff”.

“If somebody’s at risk of diabetes, there are much better things to spend money on, like a physical activity – or oily fish,” she added.

Douglas Twenefour, deputy head of care at Diabetes UK, said: “Eating a healthy, varied diet is incredibly important, and we know that certain foods – including fruits, vegetables, wholegrains, yoghurt and cheese – can help to lower your risk of type 2 diabetes.

“While omega-3 fatty acids are crucial for our overall health, it’s generally better for people with type 2 diabetes to get their intake by eating at least two portions of oily fish a week, than by taking supplements.”

But Dr Carrie Ruxton, from the industry-funded Health and Food Supplements Information Service, said: “While I would prefer people to follow the government’s advice and eat more fish, this isn’t the reality and a daily omega-3 supplement – whether from fish oil or algae – can bridge the gap.”

NHS to fund ‘life changing’ haemophilia drug

Mark Gould

Thursday, 22 August 2019

NHS England is to fund what it says will be “life changing treatment” for around 2,000 people with severe Haemophilia A, which will dramatically cut their risk of life-threatening bleeds and reduce treatment time.

The new treatment is part of a package of measures set out in the NHS Long Term Plan which will save lives through access to the most advanced medical interventions.

A new drug – emicizumab (also referred to as Hemlibra®) – mimics the action of the blood protein factor VIII to avoid uncontrolled bleeding, while cutting treatment times from multiple time-consuming infusions every week to a single injection given once-a-week or fortnight.

Many young children are affected by the condition and NHS England says parents sometimes struggle to administer the current infusion several times a month.

Simon Stevens, NHS chief executive, said: “Giving patients access to world class, trailblazing drugs and therapies is a key part of the NHS Long Term Plan which aims to save thousands more lives.

“As a parent I know that cuts and scrapes happen to kids all the time, but for many families these routine accidents can be distressing and life-threatening, so this new treatment will change lives and lift a weight from thousands of parents.

“This treatment has the potential to significantly improve the lives of people with haemophilia, especially children – reducing treatment time and even ending the dangerous bleeds which can lead to life-threatening cuts and life-changing damage.”

Liz Carroll, chief executive of The Haemophilia Society, said: “This decision is fantastic news for our community. Current treatments can require intravenous infusions multiple times a week which can place a significant burden on people with haemophilia and their carers. This decision will mean that people will have the opportunity to have treatment less frequently without intravenous access which will enable many to live their lives more freely.’’

Easy Mindful Eating Tips That Are Actually Worth Following

By now you know that what you eat is important for achieving weight loss goals. But did you know that how you eat also plays a role in your success? At its simplest, mindless eating is defined as “eating food without paying attention,” and this kind of distracted (and often emotional) eating can cause you to ignore your body’s signals that you’re full. That, in turn, can lead to weight gain, says Chris Mohr, Ph.D., R.D. (Did you know these words sabotage your weight loss goals?)

In the video below, Dr. Mohr shares his best strategies for becoming more mindful with your eating habits. Don’t have time to watch? Bookmark these tips to help you become a more mindful eater.

When you plan to eat, set a timer for 20 minutes. Take the entire 20 minutes to eat the meal, focusing on each bite so you don’t wolf it all down in five minutes.
Try eating with your non-dominant hand. This won’t feel as natural, forcing you to slow down and be more conscious about your food.
Eat silently for five minutes, thinking about what it took to produce that meal—everything from the sun’s rays to the farmer’s work, getting it from the grocery store and finally cooking the meal.
Take small bites, and thoroughly chew your food before reaching for another forkful.
Before opening the fridge or cabinet, take a breath and ask yourself, “Am I really hungry?” You can even do something else first, like reading, drinking water, or going on a short walk, to help you figure out the real answer.

A short bout of exercise enhances brain function

Most people know that regular exercise is good for your health. New research shows it may make you smarter, too.

Neuroscientists at OHSU in Portland, Oregon, working with mice, have discovered that a short burst of exercise directly boosts the function of a gene that increases connections between neurons in the hippocampus, the region of the brain associated with learning and memory.

The research is published online in the journal eLife.

“Exercise is cheap, and you don’t necessarily need a fancy gym membership or have to run 10 miles a day,” said co-senior author Gary Westbrook, M.D., senior scientist at the OHSU Vollum Institute and Dixon Professor of Neurology in the OHSU School of Medicine.

Previous research in animals and in people shows that regular exercise promotes general brain health. However, it’s hard to untangle the overall benefits of exercise to the heart, liver and muscles from the specific effect on the brain. For example, a healthy heart oxygenates the whole body, including the brain.

“Previous studies of exercise almost all focus on sustained exercise,” Westbrook said. “As neuroscientists, it’s not that we don’t care about the benefits on the heart and muscles but we wanted to know the brain-specific benefit of exercise.”

So the scientists designed a study in mice that specifically measured the brain’s response to single bouts of exercise in otherwise sedentary mice that were placed for short periods on running wheels. The mice ran a few kilometers in two hours.

The study found that short-term bursts of exercise — the human equivalent of a weekly game of pickup basketball, or 4,000 steps — promoted an increase in synapses in the hippocampus. Scientists made the key discovery by analyzing genes that were increased in single neurons activated during exercise.

One particular gene stood out: Mtss1L. This gene had been largely ignored in prior studies in the brain.

“That was the most exciting thing,” said co-lead author Christina Chatzi, Ph.D.

The Mtss1L gene encodes a protein that causes bending of the cell membrane. Researchers discovered that when this gene is activated by short bursts of exercise, it promotes small growths on neurons known as dendritic spines — the site at which synapses form.

In effect, the study showed that an acute burst of exercise is enough to prime the brain for learning.

In the next stage of research, scientists plan to pair acute bouts of exercise with learning tasks to better understand the impact on learning and memory.

7 Most Effective Exercises

Does Your Workout Really Work?
Done right, these seven exercises give you results that you can see and feel. You can you do them at a gym or at home. Watch the form shown by the trainer in the pictures. Good technique is a must. If you’re not active now, it’s a good idea to check in with your doctor first, especially if you have been diagnosed with health concerns. For example, if you have advanced osteoporosis some of these exercises may be too aggressive.
1. Walking
Why it’s a winner: You can walk anywhere, anytime. Use a treadmill or hit the streets.

How to: If you’re just starting to walk for fitness, begin with five to 10 minutes at a time. Add a few minutes to each walk until you get to at least 30 minutes per walk. Then, quicken your pace or add hills.
2. Interval Training
Why it’s a winner: Interval training boosts your fitness levels and burns more calories to help you lose weight. The basic idea is to vary the intensity within your workout, instead of going at a steady pace.

How to: Whether you walk, run, dance, or do another cardio exercise, push up the pace for a minute or two. Then back off for 2 to 4 minutes. How long your interval should last depends on the length of your workout and how much recovery time you need. A trainer can fine-tune the pacing. Repeat the intervals throughout your workout.
3. Squats
Why it’s a winner: Squats work several muscle groups — your quadriceps (“quads”), hamstrings, and gluteals (“glutes”) — at the same time.

How to: Keep your feet shoulder-width apart and your back straight. Bend your knees and lower your rear as if you were sitting down in a chair. Your weight should be evenly distributed on 3 points of your feet — heel, outaside ball, inside ball — that form a triangle. Your knees won’t stay in line with your ankles that way, but there will be less strain on other parts of your body. Add dumbbells once you can do 12 reps with good form.

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Not Just One Reason Kids Don’t Drink Enough Water

By Jennifer Clopton

July 29, 2019 — Kids need to drink plenty of water all year long — and especially in the summer — to stay healthy, hydrated, and active. But a recent study finds that on any given day, a staggering 20% of the children in the U.S. don’t drink a drop of water from tap or bottled sources.

“That doesn’t mean they don’t drink water on other days. But I think 1 in 5 kids not drinking any water on any given day is a bit surprising,” says the study’s author, Asher Rosinger, PhD, director of the Water, Health and Nutrition Laboratory at Pennsylvania State University in State College.

“Kids should be drinking water every day because water is the healthiest,” he says.

But for many parents, getting their children to drink water is not only a challenge, it is an almost impossible task. This lack of water can have deep impacts on children. It contributes to obesity, affects their performance in school, and can lead to other unhealthy habits.

“Our 6-year-old daughter drinks water, but with our son, who will be 2 in August, he won’t even drink a cup a day,” says Sarah Ford. “He drinks milk and half-water, half-juice, and that’s it. I’m at a loss as to how to get more water in him.”
She’s not alone, and this isn’t a problem parents can shrug away or ignore. The CDC says water consumption is a key part of keeping healthy, staying hydrated, and managing a healthy weight, and doctors say there are many health risks when children don’t get enough.
“Mild dehydration leads to symptoms like fatigue, headache, and poor endurance. Longer term, chronic lack of fluids affects the kidneys, the liver, the brain, and can lead to constipation, which can be very problematic,” explains Linda Friehling, MD, a pediatrician and assistant professor of general pediatrics at West Virginia University in Morgantown.

Julie A., who asked that we not use her last name, has seen her daughter negatively affected from not drinking enough water. “My daughter would get off the bus in kindergarten with her head hung, exhausted, saying she had a headache, and then she would usually vomit,” the mom says. “I would give her a bottle of water or Gatorade, and she would fall asleep on the couch, wake up an hour later, and be fine. No fever or other symptoms. It took me a while to realize she was simply dehydrated.”

The latest research indicates this is a real challenge for many. Rosinger’s study, published in JAMA Pediatrics in April 2019, analyzed 8,400 children and young adults in the U.S., showing everything they ate and drank in a 24-hour period. That data not only found that 20% of kids aren’t drinking water in a given day. It also showed that when kids didn’t drink water, they were more likely to drink sugar-sweetened beverages.

“Those kids that did not drink any plain water consumed almost twice as many calories as kids that consumed water. That is when they would drink more than 10% of their daily calories from sugary drinks,” Rosinger says.

The Penn State research team found that when children did that, they added 100 calories a day to their diet — increasing their risk of becoming overweight or obese.

“The association indicates that when kids drink water on a given day, their caloric intake from sugary drinks is half that of kids who don’t drink water,” Rosinger says. “So the recommendation that is very important for parents and pediatricians is that water should be the first beverage offered. If kids are consuming water, they get hydration from that instead of less healthy sources.”

What’s a parent to do if their children struggle or downright refuse to drink water? WebMD takes a closer look at the problem — and solutions.

Why Don’t Kids Drink Water?
There isn’t just one reason that kids don’t drink water.

“It is definitely a more complex issue than you might think,” says Erica L. Kenney, ScD, an assistant professor at the Harvard T. H. Chan School of Public Health.

Some don’t like how it tastes, and others don’t know how much their bodies need it. The problem is made worse in some places by water distrust. “It should be easy to go get a drink of water when you want one because tap water should be readily available and clean, but that’s not always the case,” she says.

A study published by Kenney’s research partners in 2019 that looked at statewide initiatives between 2016 and 2018 in 24 states and the District of Columbia found that many students attend public schools in states where not all taps are tested for lead. Kenney was also lead author of a 2017 study that found that racial, ethnic, and socioeconomic disparities in water consumption are related to differences in tap water. Kenney pointed to a 2014 study that found black and Hispanic adults were more likely to say their tap water was not safe to drink, leading them to drink less of it.

“I think something similar might be going on with children,” she says. “Kids who drank more tap water had a lower risk of being poorly hydrated, and it makes sense. If you do live in a place where your tap water is safe, abundant, and cheap, it’s the quickest and easiest route to hydration.”
Melissa Mays understands the effect of water distrust on children’s drinking habits. The mother of three and activist from Flint, MI, filed a Safe Drinking Water Act lawsuit against her state government, forcing it to replace water service lines polluted by lead as a result of the city’s water crisis.

“There is a serious distrust here of water,” she says. “It is hard, especially for younger kids. This is all they know — that water is bad. You try not to teach them water is bad, but you have to teach them to be safe.”

Mays says when water distrust is an issue, finances sometimes rule your decisions. “A lot of parents will get a 2-liter of soda because it’s easier to come by and cheaper than a case of water,” she explains. “I understand that for many families, it is a hard choice. There are a lot of hard decisions.”

Access to water at schools, camps, daycares, and preschools is another big challenge. The CDC stresses the need for students to drink water at school and has materials aimed at increasing access to it. But research published in 2016 in the Journal of Adolescent Health looked at access in 59 middle and high schools in Massachusetts. It found many schools weren’t meeting state or federal policies for minimum drinking water access for students, and in some cases, school staff may not have been accurately reporting water access.

“This is something that I think adults forget about,” Kenney says. “When you become an adult and you want a drink of water, you can generally get it. As a kid though, you are in a captive school environment, and it really depends on whether or not the school makes it easy to get the water. In some cases, there are a lot of hoops kids can have to jump through, and you can easily have a scenario where kids are going through the day and can’t get enough water to satisfy their thirst.”

Parents report many problems in school settings. Some say there are logistical and time challenges for students when it comes to getting to the bathroom. Others say water isn’t offered or encouraged in the hopes of limiting diaper changes in preschool and bathroom trips, or other distractions in older grades.

“I send my kids to school with water bottles, but they aren’t allowed to just leave them on their desk or go grab whenever. Super frustrating,” Jenn Pullen says.

“When my kids started full-time preschool last year, they did not know how to use the water fountain. They just could not get the knack of it and didn’t know how to request water from a teacher. Refillable water bottles were not allowed due to possible contamination with kids swapping bottles. My kids were coming back with stomachaches and constipation,” Rosy Estrada says.

Estrada says she’s since worked with the administration at her child’s school to raise awareness of the importance of drinking water, especially on hot days, and there are now systems in place to ensure children drink enough water throughout the day.

Understanding the Problem
So how much water should kids drink? An old adage says we should all be drinking 8 glasses a day, but in reality, guidelines vary. Some scientific publications say thirst can be your guide, but the Academy of Nutrition & Dietetics says that’s not a good idea with children.
“Children that complain often of thirst may not be drinking enough, because if you experience thirst, you may already be dehydrated,” says Kristi King, a registered dietitian nutritionist and a senior dietitian at Texas Children’s Hospital in Houston. “A great indicator is making sure their urine is pale yellow and not dark yellow. You may also be able to tell by their mood. A well-hydrated child typically is energized, where if they are dehydrated, they may be sleepy, fussy, or more moody than normal.”

CHOC Children’s, a California hospital, recommends kids drink one 8-ounce cup of water a day for every year of age. For example, 2-year-olds should drink 2 cups; 8-year-olds should have 8. Kids ages 9 and older should also have 8 cups.

The Academy of Nutrition & Dietetics says parents also need to pay close attention to how much water their children drink before, during, and after physical activity, especially in hot weather. The nutrition group recommends half a cup to 2 cups of water every 15 to 20 minutes during exercise.

Keeping children properly hydrated has long been a challenge. Kenney has been doing research in this area for several years. When she and her team looked at the hydration status of children and teens in the U.S. from 2009 to 2012 for research published in the American Journal of Public Health in 2015, about half (54.5%) of more than 4,000 participants between the ages of 6 and 19 weren’t hydrated enough.

Solutions
When it comes to solutions, advocates say you have to approach a complex problem like this in many different ways. There are organizations and advocates like the National Drinking Water Alliance working to make sure all children have access to clean and safe drinking water.

“I don’t think we have enough concrete solutions,” Kenney says. “I think there needs to be more investment in improving infrastructure for kids and families. There are a lot of homes that have outdated plumbing. We need to improve access. There also needs to be an effort to help kids trust tap water and think of it as something they drink with meals.”

Friehling says there is a role for the nation’s pediatricians to play in solving this problem, too. “From a pediatric standpoint, there is much that can be done to encourage children to drink water. I start discussing it at a very early age, between 4 and 6 months — at the same time that I discuss starting solid foods,” she explains. “I recommend that parents offer plain water, in a bottle or cup, with every meal, and drink water themselves to provide a model. Babies that have been drinking water since before they can remember are less likely to reject it later on.Experts say parents can also help boost how much water their children drink. Here are several ways to try to get ahead of the problem.

Make it a habit. The best way to get your kids drinking more water is to make it a family practice, from as early an age as possible. “I think that good habits can start in infancy,” Friehling says. “Parents can make water drinking a fun part of mealtime and break time, certainly a part of family activities and an important part of physical conditioning.”

Build it into the entire day. Have a cup of water by their bed so children can drink it before they fall asleep and when they wake up. Have a cup waiting for them in the morning when they come into the kitchen and at every meal, and make sure everyone has a cup or bottle all day around the house and when you head out.

Make water the only option. If water is the only drink available, chances are greater that kids will drink it, so remove sugary drinks from your home and see if it makes a difference.
Get water from food. King says it is important to remember that some hydration can come from fruits and vegetables. “Cucumbers, watermelon, celery, lettuce, tomatoes, and strawberries are good examples,” she says.

Get creative. Play around with how you serve water, and see if that makes a difference. Try adding fruit or fruit slices like strawberries and mint, cucumbers or berries. Add a splash of fruit juice, or make slushies with water, ice, and fruit, which can make it more fun, especially for younger children.

Laura Fuentes, a mother of three who owns a health and wellness company, has written numerous blog posts on how to get kids to drink more water. She recommends serving water really cold, in a stainless steel cup if possible and with a straw, which she says children and teens enjoy. She also likes to use frozen fruit instead of ice cubes for extra flavor. She says you can buy fresh fruit and freeze it or buy it frozen for an easier, more economical option.

“I have an easy-to-open Tupperware in the freezer with chunks of pineapple and peaches, apples, berries. Not a big frozen block of fruit, but small bites the kids can reach and grab and put in. Everyone takes what they want, and instead of an ice cube, they use that,” Fuentes says.

Start small. If your child will drink only juice, cut it down by mixing it with water. Fuentes says you can also make ice cubes out of juice and drop those in a cup of water instead of serving a whole cup of juice.

Let technology help. There are apps designed to help you remember to drink throughout the day. Smartwatches and personal activity trackers can help by offering reminders to drink. You can set reminders to go off on phones or voice-based virtual assistants like Amazon’s Alexa throughout the day, too.

Look at your own habits. Last but not least, parents and caregivers should pay attention to what they’re drinking, especially in front of the kids.

“I typically tell parents, you set the example,” Fuentes says. “If you are buying flavors for your drinks or always drinking sports drinks, you may have a problem with water too, and your child is modeling that. My kids see me walk everywhere with a cup of water, so for them, drinking water throughout the day is the norm. Children will pick up the behaviors we parents set, so modeling what we wish them to do is best.”

10 Anti-Aging Hair Care Tips

By Liesa Goins

Your hair, like your taste in music and comfort level with social media, can give away your age. Hair changes with age just like the rest of your body. “Hair follicles get smaller, sebum production declines, and some people lose pigment cells and go gray,” says Francesca Fusco, MD, assistant clinical professor of dermatology at Icahn School of Medicine at Mount Sinai in New York City.

As hormones change, the hair sheds more and grows back more slowly, causing it to thin, says David Kingsley, PhD, president of the World Trichology Society. In addition, hormones trigger a reduction in sebum production that can leave the hair feeling dryer. At the same time, pigment cells in the hair bulb wane over time, Fusco says, so hair turns gray.
But while your hair changes with age, you can update it. We asked the experts to share their best anti-aging hair care tips and tricks to keep your strands looking healthy and youthful to represent your individual style.

See Your Doctor
“Address any thinning early,” Fusco says. “We have treatments like minoxidil and Propecia that work to regrow hair,” she says. “But it’s best to rule out other causes like anemia, iron deficiency, autoimmune disorder, or the side effects of medication.”

Get the Right Cut
“As your hair thins, it’s not a bad idea to cut your hair a bit shorter, but it’s a myth that you have to cut your hair short once you reach a certain age,” says Nunzio Saviano, owner of Nunzio Saviano Salon in New York City. “You can have beautiful hair that’s below your shoulders as long as it’s cut in longer layers that move together and give the illusion of fullness.” He explains that having too many layers only emphasizes thinning texture, but longer layers hold shape and look full.

Delve Into Your Diet
“Protein and iron are the two most important things to have in your diet for healthy hair,” Fusco says. “If your diet is restricted, it can affect hair loss.” She advises asking your doctor about a blood test and a medical history to check for a deficiency in iron, vitamin D, or other minerals. Once that’s ruled out, Fusco likes the supplement Nutrafol because it contains zinc and other antioxidants that promote hair growth. “There is good research, and my patients have been happy with the results,” she says.
When in Doubt, Moisturize
Saviano tells his clients to avoid drying mousses and gels because they can cause hair to look dull and strip away shine. His trick: “I like to use mousse designed for curly hair because it tends to be moisturizing and less drying for the hair,” he says. Fusco recommends rich conditioning treatments to hydrate aging strands. She likes macadamia nut oil masks once a week.

Brush With Greatness
There’s an old wives’ tale that you should brush 100 strokes a day. That isn’t necessary, Saviano says. But gentle brushing can encourage healthy blood flow to the scalp, which is good for the hair. In fact, some research shows that scalp massage may help increase hair thickness. He suggests using a Mason Pearson soft boar bristle brush because the natural bristles are gentle on delicate strands and will distribute the hair’s natural conditioning oils.

Check the Label of Your Lather
“Look for a zinc pyrithione shampoo — it’s usually in dandruff formulas,” Fusco says. She says the ingredient is hydrating and soothing, whether you have dandruff or not, and can help anyone feeling tightness or itchiness due to decreased sebum production on the scalp.

Keep Your Cool
Heat styling can be especially damaging to thinning hair fibers. The stress can cause breakage, and since the hair is producing less sebum, you have less natural protection against the heat. Fusco warns against using too many heat tools and recommends keeping any time you expose hair to flat irons or blow dryers to a minimum.
Stay Away From Spray
Jet Rhys, owner of Jet Rhys Salon in Solana Beach, CA, tells her clients not to use too much hair spray. The drying alcohols in these stylers can cause hair to become dry and brittle.

Build Body
“There is a wonderful product called Toppik that uses vegetable fibers to camouflage areas of thinning hair,” says Mona Gohara, MD, an associate clinical professor of dermatology at Yale University. She says it’s very helpful in creating the appearance of hair thickness.

Gloss Over Gray
Gray hair naturally has a wiry, dull texture that reflects less light, Rhys says.

“Semi-permanent or permanent color can improve the texture and add body, but you don’t have to completely cover your gray,” she says. “You can just add a few ribbons to add some shine.” She also says that color has the perk of increasing volume, so it helps thinning hair feel fuller as well. “A few highlights around the temple can make a big difference in creating the look of volume and shine,” Saviano says.

Find more articles, browse back issues, and read the current issue of WebMD Magazine.

Researchers Weigh Benefits, Risks of PPIs

Reviewed by Brunilda Nazario, MD on July 31, 2019

July 31, 2019 — Rebecca Hill thought she was having a heart attack. The 59-year-old Tennessee native, now living in Wasilla, AK, went straight to the ER.

“They did some tests and found out that I had reflux,” she says. “I’ve gone through very many PPIs to try to keep mine under control.”

She was 34. Since then, Hill has used most of the prescription PPIs available and several over-the-counter versions. She hasn’t had any side effects.

But not everyone has such positive experiences. PPIs, or proton pump inhibitors, are among the most common prescription drugs and are used to treat acid reflux, heartburn, indigestion, gastroesophageal reflux disease (GERD), and stomach ulcers. They include omeprazole, lansoprazole, esomeprazole, pantoprazole and rabeprazole, PPIs work by cutting the amount of acid the stomach makes.

There are numerous case studies of the popular prescription drugs causing myriad health problems. But research results are mixed. Some studies have warned of doctors being too quick to prescribe PPIs and patients staying on them for too long. Others have found little reason for concern.

LeighAnn Miller of Knoxville, TN, was on PPIs for years without any problems.
I had initially taken Prilosec probably about 10 years ago,” she says. “It was prescribed by my primary care physician. I Just had some random heartburn and he prescribed it to me, I took it, didn’t have any issues.”

The symptoms got better 3 years later, so she stopped taking it. But the symptoms came back last July, and she was prescribed a different PPI. This time, her experience was much different.

“I began to have what appeared to be bug bites on my forearm,” says Miller, 35. “And at first, it was just a few, then it began to multiply. … I was covered in a rash from head to toe with the exception of my face for 6 months. It did not resolve completely until March.”

She stopped taking the medication as soon as the symptoms began. After several visits to dermatologists and a rheumatologist, after extensive bloodwork and a battery of tests including a biopsy, everything came back normal. Miller says she and her rheumatologist did some research and found that it could be drug-induced lupus.

According to the Lupus Foundation of America, there is a possible but not definitive link between the condition and PPIs in some people.

The experience has soured Miller on PPIs. “I’m not saying that there are not benefits to these medications, but I do think that there is more risk involved than there is benefit.”

A Very Common Drug
Just how risky it is to take these popular drugs has become a source of debate.

While the benefits to patients are undeniable, the drugs’ safety has come into sharp focus, with studies and researchers both defending and questioning the drugs’ benefits, dangers, and widespread use.

In the last few years, thousands of lawsuits have been filed, with patients claiming side effects including kidney disease and bone fractures. According to Drug Watch, a consumer advocacy group, one of the first cases is set for trial in September 2020.

A study published in May in The BMJ, a British medical journal, looked at death rates associated with PPIs.

According to lead investigator Ziyad Al-Aly, MD, an assistant professor of medicine at Washington University School of Medicine in St. Louis, the study focused on 157,000 veterans who were prescribed PPIs for the first time, following them for 10 years.
“There is a very significant body of evidence that suggests that these drugs (PPIs), when used for a long period of time, especially when they are not medically indicated, are associated with serious side effects and also associated with increased dying from specific causes — namely dying from heart disease, kidney disease, and stomach cancer.”

“There may be other risks as well,” Al-Aly continued, “But, it is important to mention in this context that PPIs are not all evil drugs. They’re also beneficial drugs when used appropriately in the right patient and for the indicated duration of time. In the right patients, these drugs actually also save lives.”

Paul Moayyedi, MD, a professor of gastroenterology at McMaster University in Ontario, Canada, says his new research on PPIs, published in early June in the American Gastroenterology Association’s journal Gastroenterology, found no need for worry.

His study was a large trial of 17,598 people whom researchers followed for 3 years. They found no evidence to support claims that PPIs cause serious diseases like chronic kidney disease, pneumonia, diabetes, and dementia.

One group was put on a PPI, and the other was given a placebo. Moayyedi says they found similar rates “of everything” between the two groups, “The rates of heart disease, stroke, pneumonia, fracture, chronic renal disease, and dementia were very similar between the two groups. Cancer rates were also similar, and all cause mortality was almost identical between the two groups.”

Moayyedi says most of the studies of PPIs are observational and therefore less reliable. They only look to understand causes and effects of these medications. But studies like his test the impact of the drugs on patients against those simply given a placebo.

“In other words, they look at people who are on PPI and people who are not on PPI … and see what happens to them over time,” he says. “These have shown increases in risk of diseases such as pneumonia, fractures. However, on average, patients in these databases who are on PPI are sicker than those who are not, and sicker people get other illnesses.”

His message to patients: “There is no harm that we can see so far.”

Folasade May, MD, director of quality improvement in gastroenterology at UCLA Health, is working on a study of the overuse of PPIs. She feels more research is needed. It’s the only way, she says, to test whether a specific medication leads to a specific outcome.

“The reason why these questions and these studies are important is that there are millions of people on PPIs,” she says. “When a medication is this common, even rare adverse effects can impact a lot of individuals. And that’s why it’s important for scientists — those in the laboratory and those that conduct human studies — to expand our knowledge on if and how PPIs are affecting our bodies in ways that we don’t want them to.”

The Consumer Healthcare Products Association represents leading manufacturers and marketers of over-the-counter medicines. In a statement to WebMD, it stands by the safety of these drugs based on years of data and use.
“More than 60 authors from 29 countries recently published results from a large randomized clinical trial confirming the safety of PPIs. Addressing a number of less rigorous studies which have raised concerns that PPIs may be associated with various health risks, the Authors concluded, ‘It is reassuring that there was no evidence for harm for most of these events other than an excess of enteric [intestinal] infections.’ ” According to the American Gastroenterological Association, which published the study in its official journal, this “new research puts safety concerns to rest.”

For 20 years, John Pandolfino, MD, has been prescribing PPIs to his patients. The division chief of gastroenterology and hepatology at Northwestern University told WebMD he’s never had a patient complain about side effects.

“In the grand scheme of things, I do think PPIs are safe, but there are studies that suggest an association between PPIs and some adverse outcomes. However, I think we have to be careful when we look at those particular studies so as to not over exaggerate the cause-and-effect potential, but also to not completely discount them.

“We know that patients that take PPIs are inherently sicker than those who do not take PPIs, and this confounder may bias studies and explain many of these associations.”

Pandolfino thinks doctors who prescribe these medicines must be more vigilant in their follow-up.

“I think this is an important conversation to be having because right now, we’re seeing new studies every week about PPIs. And since they are very similar studies, we see the same results and the same potential bias in the outcomes. This is a wake-up call for all of us to do a better job of educating patients about the risks and benefits of medicines, because all medicines have risks.”

Risks that patients are trying to process as they make decisions about whether to remain on these drugs — or not.