This is a dummy test for home page
(Reuters) – Johnson & Johnson’s blockbuster multiple myeloma drug Darzalex when added to a standard therapy regimen reduced the risk of disease progression or death by 50 percent compared with standard therapy alone in patients not previously treated for the blood cancer, according to data released on Tuesday.
Source: Reuters Medical News
(Reuters Health) – Many nursing home residents who might benefit from palliative care to make them more comfortable and improve their quality of life don’t receive it, a small U.S. study suggests.
Source: Reuters Medical News
(Reuters) – The Trump administration on Thursday proposed changes to Medicare drug plans including limits on opioid prescriptions and rules aimed at reducing drug costs for seniors, such as requiring health insurers to pass on discounts to consumers.
Source: Reuters Medical News
NEW YORK (Reuters) – Opioid drug abuse has killed more Americans than the Iraq, Afghanistan and Vietnam wars combined, and U.S. veterans and advocates this Veteran’s Day are focusing on how to help victims of the crisis.
Source: Reuters Medical News
More than half of the herbal and dietary supplements analyzed by researchers contained ingredients that differed from the list on their labels.
Source: WebMD
Two innovative new therapies for spinal muscular atrophy (SMA) type 1 have proven highly effective in clinical trials, researchers report.
Source: WebMD
Football season has begun again, and already concussions have made news. This past Saturday during Labor Day weekend, the opening weekend for most college football teams, I happened to be at the University of Texas game against the University of Maryland. I was reminded, as was everyone watching the game at the stadium or elsewhere, just how violent the sport can be. A Maryland player sustained a head injury in the third quarter while trying to make a tackle. It knocked him out of the game.
Maryland cornerback Antwaine Richardson, a sophomore from Delray Beach, Florida, had to be carted off the field after a collision with Texas’ Lil’Jordan Humphrey. Richardson, who had already recorded six solo tackles in the game, suffered a head injury and lay motionless on the field for several minutes. He was eventually carted off the field and taken to a hospital, where he was responsive and moving, according to a Maryland spokesman who reported back. Richardson currently is in concussion protocol ― as he should be ― is listed as day-to-day, and is out for an undisclosed amount of time.
Maryland’s second-year coach, DJ Durkin, while happy about getting the program’s first win over a Top 25 team in seven years, had a decidedly serious tone at his news conference Tuesday when he confirmed just how severe several injuries were that were suffered not only by Richardson, but by quarterback Tyrrell Pigrome and linebacker Jesse Aniebonam. Durkin said that quarterback Pigrome would miss the rest of the season with a torn ACL of his right knee and that Aniebonam will be out “several months” with a fractured ankle.
“Unfortunately, injuries are part of our game, and they happen,” Durkin said at his news conference.
It is well known that cigarette smoking is dangerous to one’s health and to the health of others. For some, using e-cigarettes or “vapes” has allowed them to reduce or quit the use of tobacco. I applaud those who have been able to quit smoking by using these devices. It is a step in the right direction. However, as a practicing emergency room physician, I still have some concerns about the safety of these devices. As a friend who vapes once directly, albeit somewhat inelegantly, put it, “Only a moron would believe that inhaling [stuff] into your lungs is totally harmless.”
For the sake of this article, I will use the general term ENDS (electronic nicotine delivery systems), though I acknowledge that not all e-liquids contain nicotine. This is not an attack on people who use the devices or even sell them, but simply an attempt to educate Americans on the possible risks associated with their use. For the record: I absolutely am not incentivized by any pharmaceutical companies, government agency, political organizations or anyone else.
The Royal College of Physicians published research in the Annals of Internal Medicine and actually encouraged the use of ENDS. That may be misleading, however, because the study didn’t show that vaporizers and e-cigarettes are safe, but rather that their use is safer than smoking tobacco cigarettes. It is encouraging to note, however, that they do not think vaping is a gateway to cigarette smoking. This is especially important because of the popularity of ENDS use among younger people.
Continue reading “The Alleged Dangers of Vaping — Are They Real?”
It’s pretty rare that I see someone with symptoms like those of Arizona Sen. John McCain, who went into the hospital last week to have what his docs diagnosed as a blood clot above his left eye removed. It’s the same side of the senator’s face where he had several surgeries to remove patches of melanoma – a type of skin cancer that if not treated can be deadly. Sen. McCain had his melanoma taken care of and all was good. But his doctors were in for a surprise when they saw the blood clot and abnormal tissue above it. The lab confirmed what the doctors suspected and Sen. McCain learned not only did he have a blood clot, but he also had primary glioblastoma, a very aggressive type of brain cancer. It is the most recent blow to a man who has had a history stretching back some 50 years to the Vietnam War of having to fight through some very serious physical ailments.
It’s not often that I encounter a situation in the ER where I’m diagnosing a glioblastoma, but when I’m presented with a serious condition like that in the ER, it’s immediately humbling and I have instant empathy for the patient. It’s not easy to deliver a diagnosis like that. You want to be as positive as possible, but you also understand the reality of what your patient is facing. The statistics are daunting.
Glioblastoma, or GBM, tumors are usually highly malignant. The tumor cells usually reproduce very quickly and are fed by a large network of blood vessels. The American Brain Tumor Association says, “Because these tumors come from normal brain cells, it is easy for them to invade and live within normal brain tissue.”
Treatment can help, but the condition can’t be cured. Statistically, with this kind of tumor, survival rates beyond a year and a half are uncommon. Median survival time upon first diagnosis of GBM is in the 14- to 16-month range. There are some longer-term survivors, but this type of cancer is an aggressive form, and it’s usually more extensively present in the brain than the initial diagnosis indicates.
Continue reading “Arizona Sen. John McCain’s Glioblastoma Diagnosis”
By Dr. Sudip Bose, MD, FACEP, FAAEM
We need to talk about death.
It’s certainly not easy to talk about death and dying in America. It’s immeasurably harder for one to go through a terminal illness.
Where there is life, there is death. It is inevitable for us all; yet as a society, we speak of it with hand over mouth – in hushed tones, as if the mere verbalization of it would bring it upon us. In America, we don’t deal with death very well. We want to believe that we will live to grow old and that death will be a quick and sudden event. That’s not always the case. It’s not a fun topic to talk about, and therefore we don’t talk about it nor do we plan for it properly.
We’ve got to get better about that. We’ve got to be open and honest about it. Because in the United States, we plan for death poorly or not at all. As an emergency physician, I’ve seen countless patients struck with a terminal illness, which has left families scrambling at the end of a loved one’s life trying to figure out what to do and struggling with life or death decisions. No one wants to feel like they have to step in and play God at that time. It puts family members in the position of trying to figure things out while they are in a highly emotional, stressed state. People usually don’t make the best decisions while distressed.
Family members often have a feeling of guilt if they haven’t discussed end-of-life care at some point, either before or during a terminal illness. They believe they should be doing everything possible to keep their loved one alive. But is that what the patient would want? Does it lead to a better quality of life? Is the patient unnecessarily suffering?
I once had a patient who had been declining in health for years. She was completely bedridden in her last days – couldn’t eat, go to the bathroom, etc. She was dying. It finally came to the point where she had to be put on a bipap air flow machine to keep her alive. The family knew that they didn’t want to put her on a ventilator, and they knew that if they removed the bipap machine, she wouldn’t survive. However, with a bipap machine, a patient can typically only go a maximum of about five days because it provides too much pressure and would cause damage to the patient’s face. The woman’s family ended up keeping her on the machine for the maximum amount of days. Understandably, it was difficult for the family to ultimately let their loved one go. But did it do much for the patient to lie there with a bipap mask on for the full five days? Was she just suffering even more by keeping the mask on? Were hospital resources used unnecessarily? Is that what the patient really would have wanted?
We should make an effort to talk about possible end-of-life decisions or scenarios with our loved ones. We should talk about and understand how each of the following items could play a role as a person approaches death:
Also in the context of dying and end-of-life choices, we need to talk about the subject of palliative care and get comfortable with that concept. Palliative care is defined as the act of giving medical care to someone with a serious illness without actually dealing with the cause of the condition. It’s care that’s intended to alleviate a patient’s symptoms with the goal of improving quality of life, and often is associated with relief from pain. Yet all too often in America when palliative care is mentioned as a way to ease a person’s descent into death, we use those words almost euphemistically – we use the words “palliative care” as code words for death.
I’m not talking about actively hastening a patient’s death, I’m talking about giving a patient the highest quality of life possible as he or she faces a terminal illness. In the truest sense, palliative care is appropriate at any stage of a serious illness, absolutely can work in conjunction with curative treatment and should not ever hasten death.
Here are some select bullet points regarding palliative care as defined by WHO (the World Health Organization):
I heard something recently that caught my attention. It was in the trailer for the soon-to-be-released documentary film, “Eating You Alive.” The quote came from Randy Titony, a self-described plant-based evangelist who is certified in plant-based nutrition and also is a physical therapist professional. He said, “People aren’t living longer; they’re dying longer.”
That struck me as a very interesting perspective.
If you talk to a hospital administrator or any politician in about dying in America, they might point out that a full quarter of traditional Medicare spending is provided to beneficiaries in the last year of life. They might note data that shows that spending for this cohort is four times higher for those who died at some point during the year compared to those who lived the entire year. And they’ll very likely talk about unnecessary care and overtreatment. Yet time and again, attempts to roll back such “aggressive” care are thwarted by talk of death panels and accusations of rationing care.
According to Dr. Jordan Grumet, a leading palliative care specialist and hospice medical director in Northbrook, Ill., who also writes on the subject, dying has become miserable because we eschew dignity and turn it into a high-tech, costly, drawn-out, process.
As Grumet sees it, focusing on finances is misplaced. “Improving the end of life experience is bound to fail if we focus on finances,” he said. “No one wants to feel like they are dying on the cheap.”
Instead, he believes we need to concentrate on the concept of dignity. In short, he thinks we need to die better.
I would agree. Time and again I’ve seen people unprepared for death – patient and family alike – and unprepared even for its approach and the management of issues associated with that.
A recent study by Singer et al in The Annals of Internal Medicine found that the number of people experiencing pain in the last year of life actually increased by nearly 12 percent from 1998 to 2010. And the number of people with depression increased by 26 percent.
If we focus on high-quality interventions at the end of life, things like aggressive pain control, counseling, and symptom management, and at the same time minimize low-yield treatments that increase pain and suffering – like surgery and chemotherapy, for example – could we affect and reverse those trends cited in the previous paragraph? Things like surgery, chemotherapy, diagnostic imaging ― although often utilized during the last months of life ― infrequently improve outcomes and can prolong discomfort. This should be a process of shared decision making with the family and loved ones.
The result of this sort of treatment flip, if you will, would be that patients embrace and even enjoy the last stages of life. Says Grumet: “We help them die with the same dignity that they strove to live … and, believe it or not, that might actually save our health care system some money.”
It might even have a positive effect on the course of a patient’s illness.
Palliative care providers agree. Financial concerns are very real and no one wants to make decisions based on money as someone’s life appears to be slipping away. But with the medical system’s focus on treatments regardless of cost (driven largely by medical malpractice and legal concerns) coupled with the lack of discussion families have around end-of-life issues, patients and families alike frequently do not get the kind of care they hope to get.
In an article published in 2012, Money magazine quotes Ira Byock, director of palliative medicine at Dartmouth-Hitchcock Medical Center and author of “The Best Care Possible”:
“When patients have a terminal illness, at some point more disease treatment does not equal better care.”
The key is for families to discuss end of life issues and keep communication open with their loved ones going through it. In my career, it’s been interesting to watch how people handle the end of life process – when they have any control over it. I’ve known a man in his mid-80s who was battling Parkinson’s disease who made the decision that he was ready to die. Despite the efforts of medical personnel and family members, he suddenly refused to eat, drink or take any medication. He couldn’t speak, but he knew what he was doing and family members came to understand that. He died within a day and a half.
Others will desperately cling to life, not wanting to go – hanging on without food or water for days and weeks. The importance of the possibility of one more day seeing a father, a mother, another day seeing a brother, a sister, a grandson, a son or daughter, might suddenly become a reason for living — a very powerful reason for fighting for life.
A study done by Diane E. Meier, Director of the Center to Advance Palliative Care, Professor of Geriatrics and Palliative Medicine at the Icahn School of Medicine at Mount Sinai, published in September 2011 in the Milbank Quarterly, reported the following in her findings: “Palliative care and hospice services improve patient-centered outcomes such as pain, depression, and other symptoms; patient and family satisfaction; and the receipt of care in the place that the patient chooses. Some data suggest that, compared with the usual care, palliative care prolongs life. By helping patients get the care they need to avoid unnecessary emergency department and hospital stays and shifting the focus of care to the home or community, palliative care and hospice reduce health care spending for America’s sickest and most costly patient populations.”
It’s amazing how precious life is, and how much you will fight to hold on to it when the fight is still in you, and how quickly it can go when there’s no fight left. Every patient, family, case and doctor is different. The key thing is to get education around palliative care and end of life care, have open and frank discussions, and memorialize your decisions and preferences in medical records and documents such as a living will, for example, and make sure your doctors and other care providers know what your wishes are.
From the previously cited Money magazine article: “A 2010 study in the Journal of Palliative Medicine found that only 15 to 22 percent of seriously ill elderly patients had their preferences in their medical records.” And, “studies by the Agency for Healthcare Research and Quality show that 65 to 76 percent of doctors whose patients had documents outlining end-of-life wishes weren’t aware they existed.”
Families need to engage amongst themselves and with their care providers in advance about the implementation – or not – regarding palliative care. It’s not only a treatment and financial decision, but a quality of life decision as well.
To learn more about Dr. Sudip Bose, MD, please go to SudipBose.com and visit his nonprofit TheBattleContinues.org where 100% of donations go directly to injured veterans.